Protein Modification Reagents
ABclonal Technology NRIP2 Rabbit pAb
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm.
Bioassay Systems QuantiFluo™ Pepsin Inhibitor Assay Kit, For evaluation of drugs and screening of potential inhibitors to pepsin proteases.
PEPSIN (EC 3.4.23.1) is a digestive, serine protease that hydrolyzes dietary proteins in many eukaryotic and prokaryotic organisms. Pepsin predominantly cleaves peptide chains at the amino side of the aromatic phenylalanine, tryptophan, and tyrosine amino acids. BioAssay Systems’ QuantiFluo™ Pepsin Inhibitor Assay Kit uses a fluorescein isothiocyanate (FITC)-labeled synthetic substrate. The fluorescein label is highly quenched. Upon digestion by pepsin present in the sample, the substrate is cleaved into smaller peptides, which abolishes the quenching of the fluorescence label. The fluorescence or fluorescence polarization (FP) of the FITC-labeled fragments is measured at λex/em = 485/530 nm. Inhibition is determined by the decrease in fluorescence.
Sigma Aldrich Fine Chemicals Biosciences Lysostaphin from Staphylococcus simulans recombinant, expressed in E. coli, lyophilized powder | 9011-93-2 | MFCD00131556 | 5MG
Lysostaphin from Staphylococcus simulans recombinant, expressed in E. coli, lyophilized powder | Purity: >=90% (HPLC) | 9011-93-2 | MFCD00131556 | 5MG
ABclonal Technology NRIP2 Rabbit pAb
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in cytoplasm.
![Biolegend TotalSeq™-C0382 anti-human CD177 [MEM-166]; Isotype: Mouse IgG1 κ; Reactivity: Human Cynomolgus Rhesus; Apps: PG; Size: 10 ug](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502557649.png-250.jpg)
Biolegend TotalSeq™-C0382 anti-human CD177 [MEM-166]; Isotype: Mouse IgG1 κ; Reactivity: Human Cynomolgus Rhesus; Apps: PG; Size: 10 ug
TotalSeq™-C0382 anti-human CD177 [MEM-166]; Isotype: Mouse IgG1 κ; Reactivity: Human Cynomolgus Rhesus; Apps: PG; Size: 10 ug
ABclonal Technology ZC3H7A Rabbit pAb
Enables miRNA binding activity. Involved in production of miRNAs involved in gene silencing by miRNA. Predicted to be located in nucleus.
Sigma Aldrich Fine Chemicals Biosciences Pepsin from porcine gastric mucosa | 9001-75-6 | MFCD00081840 | 10 g
Pepsin from porcine gastric mucosa | Mol Wt: 35 kDa | 9001-75-6 | MFCD00081840 | 10 g
ABclonal Technology MICU2 Rabbit pAb
Enables protein heterodimerization activity. Involved in calcium import into the mitochondrion and negative regulation of mitochondrial calcium ion concentration. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Part of uniplex complex.
Medchemexpress LLC T-Boc-N-amido-PEG15-Br | 3012589-40-8 | 98.0% | C37H74BrNO17 | 50 MG
t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Designed to selectively degrade target proteins
- For research use only
Medchemexpress LLC DSPE-PEG-azide | 90.6% | 2000 Da (average) | 25 MG
DSPE-PEG-Azide (MW 2000) is an azide-functionalized PEG-lipid supplied as a white to off-white solid for research use. It provides an azide handle for click-chemistry conjugation and is used to PEGylate lipid surfaces to modify nanoparticle and liposome properties.
- Provides azide functional group for copper-catalyzed azide-alkyne cycloaddition.
- Enables surface PEGylation of liposomes and nanoparticles to improve colloidal stability and circulation.
- Average molecular weight about 2000 Da, giving defined PEG chain length.
- Soluble in DMSO (100 mg/mL) and formulatable for in vivo dosing at ≥2.5 mg/mL with common vehicles.
- Supplied as a white to off-white solid; store powder at -20 °C.
- Reported purity approximately 90.6%.
eMolecules 2204246-03-5 | Pomalidomide-PEG3-NH-Boc | Broadpharm548.593 | C26H36N4O9 | 0.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 | 500mg | 533795541
Pomalidomide-PEG3-NH-Boc | Broadpharm | 2204246-03-5548.593 | C26H36N4O9 | 0.000 | CC(C)(C)OC(=O)NCCOCCOCCOCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12 | 500mg | 533795541
Medchemexpress LLC DOTA-PEG5-C6-DBCO | 97.9% | C49H71N7O14 | 25 MG
DOTA-PEG5-C6-DBCO is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs consist of two ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein, utilizing the intracellular ubiquitin-proteasome system for selective protein degradation. This product is for research use only.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Functions as a click chemistry reagent
- Contains a DBCO group for SPAAC with azide groups
- Molecular weight of 982.13
- Chemical formula C49H71N7O14
- Off-white to light yellow solid appearance
- High purity of 97.9%
Medchemexpress LLC DBCO-C3-amide-PEG6-NHS ester | 95.2% | 751.82 | 1 MG
DBCO-C3-amide-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions, to form efficient covalent bonds. It also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
- Click chemistry PEG reagent
- Contains an NHS ester that reacts specifically with primary amines
- Reacts under neutral or slightly alkaline conditions
- Forms efficient covalent bonds
- Contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC)